Thyroiditis

Thyroiditis is inflammation of the thyroid gland that can temporarily disrupt how it works, causing either an overactive or underactive thyroid. It has several forms - including autoimmune, viral, and postpartum types - and symptoms often change over time as the thyroid moves through different phases of inflammation and recovery. Many cases improve with monitoring and supportive treatment.

Overview | Symptoms & Causes | Diagnosis | Treatment Options

The Thyroid Gland

The thyroid is a small, butterfly-shaped gland located at the front of the neck. It produces hormones that help regulate your metabolism, energy levels, body temperature, and many other essential functions. A healthy thyroid releases these hormones in a steady, controlled way to keep the body functioning smoothly.

Thyroiditis refers to inflammation of the thyroid gland. This inflammation can disrupt how the thyroid works, sometimes causing it to release too much hormone (leading to temporary hyperthyroidism) or too little hormone (hypothyroidism). The pattern varies depending on the type of thyroiditis, and in many cases the inflammation settles over time. Thyroiditis can be short-term or long-lasting, and symptoms can range from very mild to more noticeable changes in energy, mood, and metabolism.

Understanding Thyroiditis

Thyroiditis can cause a wide range of symptoms because the inflammation may make the thyroid overactive, underactive, or fluctuate between the two.

When the thyroid becomes overactive (hyperthyroid phase):

  • Anxiety or feeling “on edge”
  • Palpitations or a fast heartbeat
  • Heat intolerance
  • Unexplained weight loss
  • Tremors or shakiness
  • Difficulty sleeping

When the thyroid becomes underactive (hypothyroid phase):

  • Fatigue or low energy
  • Weight gain
  • Feeling unusually cold
  • Dry skin or hair changes
  • Constipation
  • Low mood or “brain fog”

Types of Thyroiditis

Hashimoto's Thyroiditis (Autoimmune)

This is the most common form and occurs when the immune system mistakenly attacks the thyroid gland. Over time, this leads to reduced hormone production and permanent hypothyroidism.

Causes & risk factors: autoimmune conditions (e.g., type 1 diabetes, coeliac disease), family history of thyroid disease, female sex, and middle age.

Symptoms: usually slow onset of underactive thyroid symptoms; the gland may feel firm or enlarged.

Subacute Thyroiditis (De Quervain’s)

This form causes painful inflammation of the thyroid, often triggered by a recent viral infection. The thyroid typically becomes temporarily overactive, then underactive, before eventually returning to normal.

Causes & risk factors: preceding viral illness, seasonal peaks, and sometimes occurring after upper respiratory infections.

Symptoms: neck pain or tenderness, fever, fatigue, and the typical hyper-to-hypothyroid cycle.

Postpartum Thyroiditis

This occurs in some women within the first year after giving birth and is caused by temporary immune system changes following pregnancy. It often follows the same pattern of an overactive phase followed by an underactive phase.

Causes & risk factors: recent pregnancy, personal or family history of autoimmune disease, type 1 diabetes.

Symptoms: may mimic fatigue or mood changes associated with new motherhood, making it easy to miss.

Silent (Painless) Thyroiditis

This is similar to postpartum thyroiditis but occurs independently of pregnancy. The thyroid becomes inflamed without causing pain and often progresses through a hyper-then-hypo pattern.

Causes & risk factors: autoimmune tendencies, certain medications, or no clear trigger.

Symptoms: usually subtle, with no neck pain.

Drug-Induced Thyroiditis

Some medications can irritate or inflame the thyroid or alter hormone release. Examples include amiodarone, interferon, immune checkpoint inhibitors, and lithium.

Causes & risk factors: exposure to specific medications, underlying autoimmune conditions.

Symptoms: may mirror hyperthyroidism or hypothyroidism depending on the mechanism.

Acute (Suppurative) Thyroiditis

This is a rare but serious bacterial infection of the thyroid gland.

Causes & risk factors: bacterial spread from nearby structures, immunosuppression, congenital abnormalities of the neck.

Symptoms: severe neck pain, fever, redness, and tenderness; usually no significant changes in thyroid hormone levels.

Diagnosing Thyroiditis

Diagnosing thyroiditis involves piecing together your symptoms, physical examination findings, and a combination of blood tests and imaging. Because thyroiditis can cause hormone levels to fluctuate, your clinician will usually look at patterns rather than relying on a single result.

Blood Tests Central to diagnosis. These typically include thyroid hormone levels (TSH, free T4, and sometimes T3) to determine whether the thyroid is currently overactive or underactive. In autoimmune types - such as Hashimoto’s - antibody tests (TPO and thyroglobulin antibodies) help confirm an immune-related cause. In painful or infectious forms, inflammatory markers or white cell counts may support the diagnosis.
Ultrasound Often used to examine the gland directly. It can identify inflammation, enlargement, or textural changes typical of Hashimoto’s, detect nodules, and rule out other causes of thyroid symptoms. In subacute or painless thyroiditis, the ultrasound may show characteristic patterns that distinguish it from long-term thyroid disease.

Treatment Options

Management of thyroiditis depends on the type, severity of symptoms, and thyroid hormone levels. Some forms, such as subacute or mild autoimmune thyroiditis, may resolve on their own or cause only temporary hormone changes.

Symptom relief Pain or discomfort, particularly in subacute thyroiditis, can be managed with over-the-counter pain relievers or anti-inflammatory medications.
Hormone management If thyroid hormone levels are abnormal, your clinician may recommend short-term or longer-term medication to either replace deficient hormone (hypothyroidism) or temporarily control overactive hormone (hyperthyroidism).
Monitoring Regular follow-up with blood tests and clinical assessment helps ensure that thyroid function returns to normal or remains stable over time. Most people experience gradual improvement, though some may need ongoing treatment for chronic autoimmune thyroiditis.

Your clinician will discuss the most appropriate plan based on your symptoms, type of thyroiditis, and individual health circumstances.

How can Lanthorn help?

Thyroid Ultrasound - £300

Provides a detailed look at the thyroid gland, identifying inflammation, enlargement, or structural changes, and helps rule out other causes of thyroid problems.

Thyroid Health Blood Test - £99

Our thyroid panel measures key hormones and thyroid-specific antibodies, helping assess how well the thyroid is functioning and whether inflammation or an autoimmune process is present. This gives a clear, reliable overview of thyroid health and supports accurate diagnosis and ongoing monitoring.

Referral to a Specialist

If needed, we can refer you to an endocrinologist or other specialist for further assessment and tailored management.